THE PROJECTION FROM THE ROSTRAL ANTERIOR CINGULATE CORTEX TO THE VENTRAL TEGMENTAL AREA REGULATES 5-HT-INDUCED ITCH AVERSION AND SCRATCHING IN RATS

The projection from the rostral anterior cingulate cortex to the ventral tegmental area regulates 5-HT-induced itch aversion and scratching in rats

Many studies in Treadmill Deck humans and rodents have shown that the anterior cingulate cortex (ACC) plays a critical role in the regulation of pain-related aversion and that the projection from the rostral ACC (rACC) to the ventral tegmental area (VTA) is implicated in this modulation process.The ACC is also reported to be involved in the regulat

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The effect of opioid-sparing anesthesia regimen on short-term cognitive function after thoracoscopic surgery: a prospective cohort study

Abstract Background As type of surgery and opioids are suggested risk factors for the development of cognitive decline after surgery, we evaluated the effect of an opioid-sparing anesthesia regimen involving preoperative erector spinae block and continuous infusion of flurbiprofen on the incidence of cognitive decline after HAIR-FORCE video-assiste

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Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer

Cancer stem cells (CSCs) have been identified as a subpopulation of stem-like cancer cells EspressoCover with the ability of self-renewal and differentiation in hematological malignancies and solid tumors.Pancreatic cancer is one of the most lethal cancers worldwide.CSCs are thought to be responsible for cancer initiation, progression, metastasis,

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